North Carolina Rep. Virginia Foxx, 81, was tapped by House Speaker Mike Johnson to serve as the chairwoman of the powerful House Rules Committee, two GOP sources told ABC News, becoming the only woman to lead a House committee in the 119th Congress.

The House GOP conference voted to approve Foxx's selection during a closed-door meeting on Tuesday.

"For two decades, Dr. Foxx has been a stalwart in the House and a leader in multiple policy areas," Johnson said in a statement. "Her drive and personality have established her as among the most universally respected members of our Republican Conference. Dr. Foxx is an example of how Members should serve, and our Conference will benefit greatly with her at the helm of the influential Rules Committee."

The Rules Committee is the last stop for big-ticket legislation before it can hit the House floor for a vote. Several Republicans urged Johnson to appoint Texas Rep. Chip Roy, who often bucks leadership, to lead the committee to ensure he'd win the gavel. Meanwhile, Foxx is a staunch supporter of Johnson and getting his priorities passed through the House.

"I feel very humbled," Foxx told ABC News. "It's going to be a tough session, but I'm committed to helping make it work."

The news follows the announcement of the chairs of the 17 standing committees, which will be dominated by white men, in December. No people of color were selected.

"From securing our southern border, to unleashing American energy, to fighting to lower Bidenflation, and making our communities safe again, our Committee Chairs are ready to get to work fulfilling the American people's mandate and enacting President Trump's America-First agenda," House Majority Leader Steve Scalise said in announcing the list of chairs, who were selected by the House Republican Steering Committee. "House Republicans are heading into the 119th Congress prepared to address the issues most important to hardworking Americans and fight for meaningful legislative wins.

"I look forward to working with these strong leaders and their Committees to advance President Trump's priorities and deliver the American people the government they voted for in November," he added.

Three Republican women led House committees in the 118th Congress: Texas Rep. Kay Granger chaired the Appropriations Committee, Washington Rep. Cathy McMorris Rodgers chaired the Energy and Commerce Committee and Foxx chaired the Education and the Workforce Committee.

Neither Granger nor McMorris Rodgers ran for reelection in 2024, though Foxx did earn an 11th term in office. Foxx, 81, had been granted a waiver to lead the Education and the Workforce Committee in the 118th Congress beyond the six-year term limits the House GOP imposes, and she did not request an additional waiver. She had served as chairwoman in the 115th Congress, as well as ranking member in the 116th and the 117th. Michigan Rep. Tim Walberg will take over the chairmanship of the Education and the Workforce Committee instead.

"Chairmen of committees are very important positions, but we really do engage all the membership," House Speaker Mike Johnson said earlier this week ahead of the selections. "We have extraordinary women serving in Congress and in the Republican Conference. In fact, we elected some really strong women in the upcoming freshmen class.

"We value those voices. And everybody has an equal say at the table," he noted. "These are thoughtful elections. We have an embarrassment of riches, frankly."

Florida Rep. Brian Mast, a close Trump ally, will lead the House Foreign Affairs Committee. Ohio Rep. Jim Jordan will continue to lead the Judiciary Committee, Kentucky Rep. James Comer will continue to lead the Oversight Committee and Missouri Rep. Jason Smith will continue to lead the powerful Ways and Means Committee.

"Very fitting in the MAGA Era - No Women Need Apply," former Virginia Rep. Barbara Comstock, a Republican, posted ahead of the final selections in December when no women had been selected.

The Republican Party will have a trifecta after Trump's inauguration with control of the House, Senate, and White House, but the razor-thin majority of 220 Republicans to 215 Democrats in the House will leave little room for dissent, especially with two members of the House GOP set to be nominated for posts in the Trump administration and the resignation of Florida Rep. Matt Gaetz.

"After four years of suffering under the radical policies of the Biden-Harris Administration and a Democrat-controlled Senate, the American people made clear they are ready for a change," Scalise added. "With Republicans taking control of the White House, Senate, and House, it is imperative we are in position to move President Trump's agenda efficiently and thoughtfully so we can quickly restore our nation to greatness."

ABC News' John Parkinson contributed to this report.