Sen. Kyrsten Sinema (D-Ariz.) is back in Arizona on Friday as Democrats and the White House try to work out an agreement to unlock a stalled bipartisan infrastructure bill, which she spearheaded, and a sweeping social spending bill, where she's a key holdout.

Sinema, according to a spokesman, returned to Arizona for a "medical appointment" on Friday but is continuing "remote negotiations with the White House."

Sinema and her staff offered the "White House continued discussions and negotiations" for Friday, the spokesman added, and the two sides connected on Friday afternoon.

Sinema's return to her home state comes after she and Sen. Joe Manchin (D-W.Va.) met with White House domestic policy adviser Susan Rice and senior adviser Brian Deese late into Thursday night in a basement office in the Capitol.

Democratic leadership and the White House are hoping that they can reach an agreement with Sinema and Manchin on a framework for the reconciliation bill that would convince House progressives to vote for the Senate-passed bipartisan infrastructure bill, after House Democratic leadership delayed a vote on Thursday night.

Both Manchin and Sinema have warned that they can't support a $3.5 trillion bill, the size that House Democrats have crafted. Manchin said this week that he's willing to go as high as $1.5 trillion, while Sinema has not specified a top-line number.

The Senate largely left town on Thursday night until Monday. A spokeswoman for Manchin didn't respond to a question on Friday about if he had stayed in Washington, D.C., but Manchin told reporters as he left the Capitol on Thursday night that "I should be around" and that he's "not leaving."

The House is still in Washington, D.C., with President Biden heading to Capitol Hill to meet with Democrats. The timing of a vote on the Senate-passed infrastructure bill is in limbo, with progressives threatening to vote it down if Pelosi brings it to the floor without an agreement worked out on reconciliation.

House leadership also hasn't said if they'll keep their members in Washington, D.C., through the weekend. But Sinema, The New York Times reported, has a fundraiser in Arizona over the weekend. 

House Democrats downplayed Sinema's absence, noting that they could connect with her even if that wasn't in person.

Rep. Hakeem Jeffries (N.Y.), the House Democratic caucus chairman, appeared unconcerned that Sinema wasn't in Washington on Friday.

“I mean, that probably would’ve been problematic in 1800, when we otherwise would not have been able to reach her," Jeffries said.

Cristina Marcos contributed. Updated at 4:56 p.m.